Published March 2018 | Version v1
Journal article Metadata-only

Surface enhanced Raman detection of the colon cancer biomarker cytidine by using magnetized nanoparticles of the type Fe3O4/Au/Ag

Creators

  • 1. Shanghai Normal University, The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry (China)

Description

Cytidine is regarded as an early marker of colon cancer. The authors describe a surface enhanced Raman scattering (SERS) technique to detect trace levels of cytidine in urine. The Raman band at 784 cm−1 can be acquired best. Compared to earlier methods, an improvement in detection sensitivity by a factor of 6.2 × 105 is achieved by using a magnetically induced method in which cytidine is captured in the vicinity of the SERS hot spots of the type Fe3O4/Au/Ag. Cytidine can be quantified at 1 nM levels by this method which is simple and reliable. .

Additional details

Identifiers

DOI
10.1007/s00604-017-2666-5;

Publishing Information

Journal Title
Mikrochimica Acta
Journal Volume
185
Journal Issue
3
Journal Page Range
p. 1-7
ISSN
0026-3672
CODEN
MIACAQ

INIS

Country of Publication
Austria
Country of Input or Organization
Austria
INIS RN
50047040
Subject category
S77: NANOSCIENCE AND NANOTECHNOLOGY; S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
Descriptors DEI
BIOLOGICAL MARKERS; CYTIDINE; FERRITES; GOLD; IRON OXIDES; LARGE INTESTINE; NANOCHEMISTRY; NANOPARTICLES; NEOPLASMS; RAMAN EFFECT; RAMAN SPECTROSCOPY; SILVER; URINE
Descriptors DEC
AZINES; BIOLOGICAL MATERIALS; BIOLOGICAL WASTES; BODY; BODY FLUIDS; CHALCOGENIDES; CHEMISTRY; DIGESTIVE SYSTEM; DISEASES; ELEMENTS; FERRIMAGNETIC MATERIALS; GASTROINTESTINAL TRACT; HETEROCYCLIC COMPOUNDS; INTESTINES; IRON COMPOUNDS; LASER SPECTROSCOPY; MAGNETIC MATERIALS; MATERIALS; METALS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; OXIDES; OXYGEN COMPOUNDS; PARTICLES; PYRIMIDINES; RIBOSIDES; SPECTROSCOPY; TRANSITION ELEMENT COMPOUNDS; TRANSITION ELEMENTS; WASTES

Optional Information

Copyright
Copyright (c) 2018 Springer-Verlag GmbH Austria, part of Springer Nature