Published December 2015 | Version v1
Journal article

In Vitro Antioxidant Evaluation of Some Mannich Bases which Contain Bis-1,2,4 -Triazole Derivative

  • 1. Firat Univ., Elazig (Turkey). Keban Vocational School of Higher Education
  • 2. Firat Univ., Elazig (Turkey). Dept. of Chemistry
  • 3. Cumhuriyet Univ., Sivas (Turkey). Dept. of Biometrics and Genetics
  • 4. Firat Univ., Elazig (Turkey). Dept. of Physiology
  • 5. Usak Univ., Usak (Turkey). Faculty of Medicine

Description

This study aims to examine the antioxidant effects of some Mannich bases containing bis-1, 2, 4 triazole, which are synthesized afresh. The antioxidant activities of the derivatives were measured using different methods in this study, including reducing power capacity, metal chelating activity, superoxide anion radicals scavenging activity, H/sub 2/ O/sub 2/ scavenging activity and hydroxyl radical scavenging. As a result, derivatives had efficient antioxidant and free radical scavenging activity when compared to ascorbic acid, BHT and alpha-tocopherol as associated antioxidants. (author)

Additional details

Publishing Information

Journal Title
Journal of the Chemical Society of Pakistan
Journal Volume
37
Journal Issue
6
Journal Page Range
p. 1192-1204
ISSN
0253-5106

INIS

Country of Publication
Pakistan
Country of Input or Organization
Pakistan
INIS RN
47074190
Subject category
S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
Descriptors DEI
ANTIOXIDANTS; CHELATING AGENTS; PH VALUE; RADICALS; SCAVENGING; SYNTHESIS; TRIAZOLES
Descriptors DEC
AZOLES; HETEROCYCLIC COMPOUNDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS