Published April 18, 2008
| Version v1
Journal article
A relationship between solvent viscosity and biomolecule picosecond thermal fluctuations
- 1. Dipartimento di Fisica dell'Universita di Perugia, and INFM-CRS SOFT Unita di Perugia, Via A. Pascoli, I-06123 Perugia (Italy) and CEMIN - Centro di Eccellenza per i Materiali Innovativi e Nanostrutturati, c/o Dipartimento di Chimica dell'Universita di Perugia, Via Elce di Sotto 8, I-06123 Perugia (Italy)
- 2. CNR-INFM CRS SOFT, I-00185 Roma (Italy) c/o Institut Laue-Langevin, Rue Jules Horowitz 6, F-38042 Grenoble (France)
- 3. CEMIN - Centro di Eccellenza per i Materiali Innovativi e Nanostrutturati, c/o Dipartimento di Chimica dell'Universita di Perugia, Via Elce di Sotto 8, I-06123 Perugia (Italy)
- 4. Dipartimento di Fisica dell'Universita di Perugia, and INFM-CRS SOFT Unita di Perugia, Via A. Pascoli, I-06123 Perugia (Italy)
Description
Through elastic neutron scattering measurements, we investigated the picosecond dynamics of DNA in the hydrated powder state or embedded in glycerol glassy matrix from 20 K to 300 K. We calculated the relaxational contribution of the mean square displacements (MSD) of DNA hydrogen atoms. We found the existence of a linear relationship between the inverse of the biomolecule relaxational MSD and the logarithm of the bulk viscosity of the surrounding environment. From the comparison with the case of lysozyme in the same environments, for which the validity of the relationship was already verified, possible differences and analogies concerning the biomolecule-to-solvent dynamical coupling can be stressed
Availability note (English)
Available from http://dx.doi.org/10.1016/j.chemphys.2007.07.022Additional details
Identifiers
- DOI
- 10.1016/j.chemphys.2007.07.022;
- PII
- S0301-0104(07)00316-3;
Publishing Information
- Journal Title
- Chemical Physics
- Journal Volume
- 345
- Journal Issue
- 2-3
- Journal Page Range
- p. 219-223
- ISSN
- 0301-0104
- CODEN
- CMPHC2
Conference
- Title
- 4. general integrated infrastructure initiative for neutron scattering and muon spectroscopy meeting
- Dates
- 7-10 Oct 2006
- Place
- Taormina (Italy)
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 40033772
- Subject category
- S75: CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- DNA; FLUCTUATIONS; GLYCEROL; HYDROGEN; LYSOZYME; NEUTRON DIFFRACTION; NEUTRON SPECTROSCOPY; TEMPERATURE RANGE 0013-0065 K; TEMPERATURE RANGE 0065-0273 K; TEMPERATURE RANGE 0273-0400 K; VISCOSITY
- Descriptors DEC
- ALCOHOLS; COHERENT SCATTERING; DIFFRACTION; ELEMENTS; ENZYMES; GLYCOSYL HYDROLASES; HYDROLASES; HYDROXY COMPOUNDS; NONMETALS; NUCLEIC ACIDS; O-GLYCOSYL HYDROLASES; ORGANIC COMPOUNDS; PROTEINS; SCATTERING; SPECTROSCOPY; TEMPERATURE RANGE; VARIATIONS
Optional Information
- Copyright
- Copyright (c) 2007 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.