Modulatory Role of Aloe vera on Gamma Irradiation Induced Histological Changes in Different Tissues of Rats
Creators
- 1. Health Radiation Research Department, National Centre for Radiation Research and Technology Cairo (Egypt)
Description
Aloe Vera is known for its wide medicinal properties. This study was performed to evaluate the role of Aloe vera (Aloe barbadensis Miller) in the amelioration of the histological disorders that occurr in different tissues of albino rats exposed to 7 Gy whole body gamma irradiation, delivered as a single dose. Aloe vera (leaf juice filtrate) was supplemented daily to rats (0.25 ml/kg b wt/day) by gavage, 5 days before irradiation and 10 days after irradiation. Experimental investigations performed 7 and 10 days after exposure to radiation showed that Aloe vera treatment has significantly improved the radiation-induced inflammation, haemorrhage, widening and dilated blood vessela, necrosis, atrophy sloughing in liver, spleen and small intestine (jejenum) tissues of irradiated rats. It is concluded that the synergistic relationship between the elements found in the leaf of Aloe vera could be a useful adjunct for maintaining the integrity of histological architecture
Additional details
Publishing Information
- Journal Title
- Egyptian Journal of Radiation Sciences and Applications
- Journal Volume
- 18
- Journal Issue
- 1
- Journal Page Range
- p. 97-115
- ISSN
- 1110-0303
INIS
- Country of Publication
- Egypt
- Country of Input or Organization
- Egypt
- INIS RN
- 36037011
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- ALOE; ANIMAL TISSUES; ARTERIES; ATROPHY; BLOOD VESSELS; CYTOPLASM; GAMMA RADIATION; HISTOLOGICAL TECHNIQUES; LYMPHATIC SYSTEM; NECROSIS; PLANT TISSUES; RATS; SMALL INTESTINE
- Descriptors DEC
- ANIMALS; BLOOD VESSELS; BODY; CARDIOVASCULAR SYSTEM; CELL CONSTITUENTS; DIGESTIVE SYSTEM; ELECTROMAGNETIC RADIATION; GASTROINTESTINAL TRACT; INTESTINES; IONIZING RADIATIONS; LILIOPSIDA; MAGNOLIOPHYTA; MAMMALS; MEDICINAL PLANTS; ORGANS; PATHOLOGICAL CHANGES; PLANTS; RADIATIONS; RODENTS; VERTEBRATES