Synthesis and antimicrobical activity of composite oxides nanoparticles based on ZnO

It should be noted that zinc oxide nanoparticles have increased antibacterial activity. ZnO/Me composite nanoparticles have a more pronounced antimicrobial effect in comparison with monometallic nanoparticles obtained by similar conditions. In present work ZnO/Ag and ZnO/CuO composite nanoparticles were obtained by the electrical explosion of Zn and Cu or Zn and Ag wires in oxygen containing atmosphere. Composite nanoparticles were characterized by transmission electron microscopy, XRD analysis and micro electrophoresis. Antibacterial activity of composite nanoparticles against Gram-positive E.coli and Gram-negative MRSA was studied. The as-synthesized nanoparticles demonstrated excellent bactericidal effect due to their unique properties including not only components additive effect but also synergetic one. (paper)