Published 1996 | Version v1
Miscellaneous Metadata-only

131I-Lipiodol labelling and its clinical application

Creators

  • 1. Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil)
  • 2. Sao Paulo Univ., SP (Brazil). Centro de Medicina Nuclear

Description

Lipiodol-131 I is used as a contrast agent in lymphangiography and it also acts as an immunosupress agent for the endolynphatic irradiation in patients who need renal transplant. The labelling of lipiodol with I-131 occurs by isotopic exchange and the separation of the labelled 131 I is carried out through a solvent extraction technique. Quality control tests (radiochemical, biological, microbiological and pyrogenic) were performed, and the result was that the compound is suitable for clinical application. The labelling yield varied from 70 to 85%. Doses of 925 MBq were injected into the dorsal paw of the patient's feet which permitted the visualization of all the lymphatic region. (author)

Availability note (English)

Available from the library of the Brazilian Nuclear Energy Commission, Rio de Janeiro

Additional details

Additional titles

Original title (Portuguese)
Marcacao do lipiodol com

Publishing Information

Imprint Pagination
3 p.

Conference

Title
6. General congress on nuclear energy
Original Conference Title
6. Congresso geral de energia nuclear
Dates
27 Oct - 1 Nov 1996
Place
Rio de Janeiro, RJ (Brazil)

INIS

Country of Publication
Brazil
Country of Input or Organization
Brazil
INIS RN
31031871
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY; S62: RADIOLOGY AND NUCLEAR MEDICINE;
Resource subtype / Literary indicator
Conference, Non-conventional Literature
Descriptors DEI
BIOMEDICAL RADIOGRAPHY; BLOOD VESSELS; IMAGES; IMMUNOSUPPRESSIVE DRUGS; IMPURITIES; IODINE 131; LABELLING; LIPIODOL; PATIENTS; RADIOCHEMISTRY; STABILITY; UROGENITAL SYSTEM DISEASES
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARDIOVASCULAR SYSTEM; CHEMISTRY; CONTRAST MEDIA; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPES; MAMMALS; MAN; MEDICINE; NUCLEI; ODD-EVEN NUCLEI; OILS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC IODINE COMPOUNDS; ORGANS; OTHER ORGANIC COMPOUNDS; PRIMATES; RADIOISOTOPES; VERTEBRATES

Optional Information

Notes
5 refs., 4 figs., 2 tabs.