Published 1990 | Version v1
Book

The role of high performance liquid chromatography in radiochemical/radiopharmaceutical synthesis and quality assurance

  • 1. Mount Sinai Medical Center, Miami Beach, FL (USA)
  • 2. Univ. of Texas Health Science Center, Houston (USA)

Description

The usefulness of HPLC in all areas of radiopharmaceutics has been demonstrated in numerous laboratories, particularly in the development of in-house radiopharmaceuticals for SPECT and PET. HPLC continues to be a powerful tool in preparation and quality assurance (QA) as illustrated in such areas as chemical and radiochemical identification; product separation and isolation; preparative scale purification; and specific activity determination. A review of established HPLC techniques in radiopharmaceutics will be presented. Examples from the literature as well as newer applications will be used in an attempt to assess and define the present-day role of HPLC in the preparation of radiochemicals and radiopharmaceuticals with emphasis on QA

Additional details

Publishing Information

Publisher
American Chemical Society.
Imprint Place
Washington, DC (USA)
Imprint Title
American Chemical Society, Division of Nuclear Chemistry and Technology
Imprint Pagination
56 p.
Journal Page Range
p. 43.

Conference

Title
200. American Chemical Society national meeting.
Dates
26-31 Aug 1990.
Place
Washington, DC (USA).

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
22016255
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Resource subtype / Literary indicator
Conference
Descriptors DEI
LIQUID COLUMN CHROMATOGRAPHY; QUALITY ASSURANCE; RADIOCHEMISTRY; RADIOPHARMACEUTICALS; REVIEWS; SYNTHESIS; USES
Descriptors DEC
CHEMISTRY; CHROMATOGRAPHY; DOCUMENT TYPES; DRUGS; LABELLED COMPOUNDS; MATERIALS; RADIOACTIVE MATERIALS; SEPARATION PROCESSES

Optional Information

Notes
Paper NUCL 138.
Secondary number(s)
CONF-900802--.