Leucocyte status in patients during radiotherapy by linear accelerator
Creators
- 1. All India Institute of Medical Sciences, New Delhi (India). Dept. of Radiation Oncology
Description
Alterations in the various leucocyte components in cancer patients undergoing radiotherapy by linear accelerator and telecobalt unit were evaluated. The change was found to be dependent on the dose rate, which was 300 cGy/min in linear accelerator and 127 cGy/min in telecobalt. Apart from the monocyte which registered a significant rise in patients on linear accelerator (p 0.01) all other components showed a downward trend as compared to their pre-treatment level. Patients on telecobalt had marked deterioration of these parameters. These findings indicate that higher dose rate radiotherapy preserves the cellular components engaged in anticancer immune mechanism and hence an improvement in the prognosis may be expected. (author). 11 refs., 2 tabs
Additional details
Publishing Information
- Journal Title
- Indian Journal of Radiology and Imaging
- Journal Issue
- suppl.pt.1
- Journal Page Range
- p. 324-327.
- ISSN
- 0970-2016
- CODEN
- IJRIES
INIS
- Country of Publication
- India
- Country of Input or Organization
- India
- INIS RN
- 24053875
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE; S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; BONE MARROW; CELL CONSTITUENTS; COBALT 60; DOSE RATES; FRACTIONATED IRRADIATION; GAMMA RADIATION; IMMUNITY; LINEAR ACCELERATORS; LYMPHOCYTES; MONOCYTES; NEOPLASMS; RADIOTHERAPY
- Descriptors DEC
- ACCELERATORS; ANIMAL CELLS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY; BODY FLUIDS; COBALT ISOTOPES; CONNECTIVE TISSUE CELLS; DISEASES; ELECTROMAGNETIC RADIATION; HEMATOPOIETIC SYSTEM; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IONIZING RADIATIONS; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LEUKOCYTES; MATERIALS; MEDICINE; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; SOMATIC CELLS; THERAPY; TISSUES; YEARS LIVING RADIOISOTOPES