Published January 2002
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Synthesis of 4-[18F]fluorobenzaldehyde - an important labelling moiety in 18F chemistry
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Description
The synthesis of 4-[18F]fluorobenzaldehyde (4-[18F]FBA) was investigated. Starting from 4-trimethylammoniumbenzaldehyde triflate (TMABATf), 4-[18F]FBA was obtained in radiochemical yields of up to 78%. 4-nitrobenzaldehyde was also tested as a precursor, but without success. (orig.)
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Publishing Information
- Imprint Title
- Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual report 2001
- Imprint Pagination
- 113 p.
- Journal Page Range
- p. 58
- ISSN
- 1437-322X
- Report number
- FZR--340
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 35062597
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- BENZALDEHYDE; CHEMICAL PREPARATION; CHEMICAL REACTION YIELD; FLUORINE 18; FLUORINE COMPOUNDS; LABELLED COMPOUNDS
- Descriptors DEC
- ALDEHYDES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; FLUORINE ISOTOPES; HALOGEN COMPOUNDS; HOURS LIVING RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LIGHT NUCLEI; NANOSECONDS LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; RADIOISOTOPES; SYNTHESIS; YIELDS