analysis of the antioxidantive qualities of sperm after total body X-irradiation of animals

Dose-dependant up-regulation of antioxidant enzymatic activity of seminal fluid on the 10th day after exposure to 1.0-7.0 Gy dose range of total X-ray irradiation was shown. This effect was accompanied by the decrease of free thiols concentration, from the one hand, and both TBA-active products and oxidized glutathione contents elevation, from the other hand. This seminal plasma state was shown to be temporal and partially normalized on 90th day after exposure.Total X-ray irradiation of rabbits leads to significant up-regulation of antioxidant processes of both enzymatic and non-enzymatic type on the 10th day after radiation exposure in seminal plasma. This effect was shown to be dose-dependent. Then antioxidant activity dropped and metabolic activities gradually normalized according to studied parameters within 9- days after exposure in 1.0 and 2.0 Gy