Published 1989
| Version v1
Journal article
Ultraviolet mutagenesis and the SOS response in Escherichia coli: A personal perspective
Description
The study of ultraviolet (UV) mutagenesis in Escherichia coli began with the assumption that genes were likely to be changed at the instant of photon absorption. Over many decades, it became clear that postirradiation cellular activities, including enzymatic DNA repair of UV photo products and error-prone modes of tolerating unrepaired DNA lesions can exert profound influences on the mutagenic outcome of irradiation. Current study focusses on the molecular details of radiation-induced translesion DNA replication as the final event in UV mutagenesis
Additional details
Publishing Information
- Journal Title
- Environmental and Molecular Mutagenesis
- Journal Issue
- p. 30-34
- Series
- Environ. Mol. Mutagen.
- ISSN
- 0893-6692
- CODEN
- EMMUE
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 21018771
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- DNA REPAIR; ESCHERICHIA COLI; GENETIC RADIATION EFFECTS; HISTORICAL ASPECTS; MUTAGENESIS; MUTAGENS; MUTATIONS; RADIATION EFFECTS; ULTRAVIOLET RADIATION
- Descriptors DEC
- BACTERIA; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BIOLOGICAL RECOVERY; BIOLOGICAL REPAIR; ELECTROMAGNETIC RADIATION; GENETIC EFFECTS; MICROORGANISMS; RADIATIONS