New scintigraphic method for the quantitive measurement of enerogastric reflux

A modified, quantitative cholescintigraphic method for the assessment of enterogastric reflux has been developed. The distribution of the hepatobiliary tracer sup(99m)Tc-Hida is continuously recorded by a computer for 1 h after intravenous injection of the substance. With the patient still in a supine position under the gamma camera two administrations were made orally: 1) A gelatin capsule containing a known amount of sup(99m)Tc- pertechnetate, which was studied, making possibly a determination of the relation between registered counts and known acitivity: and 2) sup(99m)Tc-labelled Albu-Res in water, which identified the gastric region. An intravenous injection of synthetic cholecystokinin (Kinevac) 25 min after Hida administration emptied the biliary system into the duodenum in a controllable manner. The lower limit of reflux detected by this method was about 0,5% of the Hida dose given. (Auth.)