Clinical significance of determination of changes of serum TNF-α, IL-6 and IL-8 levels after treatment in patients with chronic prostatitis
Creators
- 1. Department of Laboratory, Donghai County People's Hospital, Jiangsu, Donghai (China)
Description
Objective: To explore the significance of changes of serum TNF-α, IL-6 and IL-8 levels after treatment in patients with chronic prostatitis. Methods: Serum TNF-α, IL-6 and IL-8 levels (with RIA) were detected both before and after treatment in 42 patients with chronic prostatitis as well as in 35 controls. Results: Before treatment, the serum TNF-α, IL-6 and IL-8 levels in the patients were significantly higher than those in controls (P<0.01). After 2 weeks of treatment, the IL-6 and IL -8 levels, though dropped markedly, remained significantly higher than those in controls (P<0.05). However, the serum TNF-α levels were not much different from those in controls. Conclusion: TNF-α, IL-6 and IL-8 could take part in the pathogenesis of chronic prostatitis in various ways and determination of these levels is clinically important. (authors)
Additional details
Publishing Information
- Journal Title
- Journal of Radioimmunology
- Journal Volume
- 21
- Journal Issue
- 5
- Journal Page Range
- p. 408-410
- ISSN
- 1008-9810
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 41053221
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BLOOD SERUM; LYMPHOKINES; PATHOGENESIS; PROSTATE; RADIOIMMUNOASSAY; RESPONSE MODIFYING FACTORS; THERAPY; UROGENITAL SYSTEM DISEASES
- Descriptors DEC
- BIOASSAY; BIOLOGICAL MATERIALS; BLOOD; BLOOD PLASMA; BODY; BODY FLUIDS; DIAGNOSTIC TECHNIQUES; DISEASES; GLANDS; GROWTH FACTORS; IMMUNOASSAY; ISOTOPE APPLICATIONS; MALE GENITALS; MATERIALS; MEDICINE; MITOGENS; ORGANIC COMPOUNDS; ORGANS; PROTEINS; RADIOASSAY; RADIOIMMUNODETECTION; TRACER TECHNIQUES
Optional Information
- Notes
- 1 tab., 9 refs.