Published April 18, 2008 | Version v1
Journal article Metadata-only

Neutron scattering and HPLC study on L-ascorbic acid and its degradation

Creators

  • 1. Department of Organic and Biological Chemistry, University of Messina, Messina (Italy)
  • 2. Department of Physics, University of Messina, Messina (Italy)
  • 3. Department of Clinical and Experimental Medicine and Pharmacology, University of Messina, Messina (Italy)

Description

The present paper shows a systematic dynamic and kinetic study on L-ascorbic acid and its degradation at high temperature. The neutron scattering study allows, through the behavior of quasi-elastic neutron scattering (QENS) spectra, to characterize the diffusive dynamics of L-ascorbic acid in water mixtures. Ascorbic acid undergoes degradation process at high temperature, but the presence of trehalose in solution markedly avoids ascorbic acid loss enhancing its t1/2 (half life time), as determined by high performance liquid chromatography (HPLC)

Availability note (English)

Available from http://dx.doi.org/10.1016/j.chemphys.2007.07.006

Additional details

Identifiers

DOI
10.1016/j.chemphys.2007.07.006;
PII
S0301-0104(07)00277-7;

Publishing Information

Journal Title
Chemical Physics
Journal Volume
345
Journal Issue
2-3
Journal Page Range
p. 191-195
ISSN
0301-0104
CODEN
CMPHC2

Conference

Title
4. general integrated infrastructure initiative for neutron scattering and muon spectroscopy meeting
Dates
7-10 Oct 2006
Place
Taormina (Italy)

INIS

Country of Publication
Netherlands
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
40033768
Subject category
S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ASCORBIC ACID; DIFFUSION; HALF-LIFE; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; NEUTRON DIFFRACTION; SPECTRA; WATER
Descriptors DEC
CHROMATOGRAPHY; COHERENT SCATTERING; DIFFRACTION; HYDROGEN COMPOUNDS; LIQUID COLUMN CHROMATOGRAPHY; OXYGEN COMPOUNDS; SCATTERING; SEPARATION PROCESSES; VITAMINS

Optional Information

Copyright
Copyright (c) 2007 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.