Published December 2013 | Version v1
Journal article Metadata-only

Observation for biological distribution of 99mTc-gelatin in mice

Creators

  • 1. Institute of Radiation Medicine, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin (China)

Description

Objective: To explore the possibility of 99mTc-gelatin acting as imaging reagent for glomerular filtration. Methods: 99mTc-gelatin was prepared by using 99Mo-99mTc generator. Rate of Radioactive uptake and radiocounting of 99mTc-gelatin were detected in heart, liver, lung, spleen, kidney and stomach of mice. Results: High uptake rate and long holding period of 99mTc-gelatin were discovered in kidney, but the removal in blood was very fast. Conclusion: 99mTc-gelatin was hopeful to be a kind of imaging reagent of glomerular filtration. (authors)

Additional details

Publishing Information

Journal Title
Chinese Journal of Radiological Health
Journal Volume
22
Journal Issue
6
Journal Page Range
p. 661-662
ISSN
1004-714X

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
51068155
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BLOOD; DISTRIBUTION; FILTRATION; GELATIN; HEART; KIDNEYS; LIVER; LUNGS; MICE; MOLYBDENUM 99; SPLEEN; STOMACH; TECHNETIUM 99; UPTAKE
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BODY; BODY FLUIDS; CARDIOVASCULAR SYSTEM; COLLOIDS; DAYS LIVING RADIOISOTOPES; DIGESTIVE SYSTEM; DISPERSIONS; EVEN-ODD NUCLEI; GASTROINTESTINAL TRACT; GLANDS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MATERIALS; MOLYBDENUM ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANS; PROTEINS; RADIOISOTOPES; RESPIRATORY SYSTEM; RODENTS; SEPARATION PROCESSES; TECHNETIUM ISOTOPES; VERTEBRATES; YEARS LIVING RADIOISOTOPES

Optional Information

Notes
2 tabs., 5 refs.