Published October 1986 | Version v1
Journal article Metadata-only

Tumour localization of samarium-153 chelates in malignant melanoma

Creators

  • 1. Australian Atomic Energy Commission Research Establishment, Lucas Heights
  • 2. Murdoch Univ. (Australia)
  • 3. Fremantle Hospital (Australia)

Description

Tumour affinity of radiolanthanides prompted an investigation of uptake of Sm-153 chelates in B16 murine melanoma. Samarium-153 chelates of DTPA, HEDTA, 1DA, HIDA, PIH (pyridoxal isonicotinoyl hydrazone), PBH (pyridoxal benzoyl hydrazone) and BZ (benzimidazole) were prepared and their behaviour was compared with that of Sm-153 chloride and citrate. (author)

Additional details

Publishing Information

Journal Title
J. Labelled Compd. Radiopharm.
Journal Volume
23
Journal Issue
10-12
Series
J. Labelled Compd. Radiopharm.
Journal Page Range
1367-1369
ISSN
0362-4803
CODEN
JLCRD

Conference

Title
6. international symposium on radiopharmaceutical chemistry.
Dates
29 Jun - 3 Jul 1986.
Place
Boston, MA (USA).

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
18082652
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Resource subtype / Literary indicator
Conference
Descriptors DEI
CHELATES; CHELATING AGENTS; CHEMICAL PREPARATION; DTPA; HEDTA; MELANOMAS; MICE; RADIOPHARMACEUTICALS; SAMARIUM 153; TISSUE DISTRIBUTION; UPTAKE
Descriptors DEC
AMINO ACIDS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CARBOXYLIC ACIDS; COMPLEXES; DAYS LIVING RADIOISOTOPES; DISEASES; DISTRIBUTION; DRUGS; EVEN-ODD NUCLEI; HYDROXY ACIDS; INTERMEDIATE MASS NUCLEI; ISOTOPES; LABELLED COMPOUNDS; MAMMALS; MATERIALS; NEOPLASMS; NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RADIOPROTECTIVE SUBSTANCES; RARE EARTH NUCLEI; RESPONSE MODIFYING FACTORS; RODENTS; SAMARIUM ISOTOPES; SYNTHESIS; VERTEBRATES