Dilated cardiomyopathy reversibility in Sheehan's syndrome: a case report

Sheehan's syndrome, discovered in 1937 by Harold Leeming Sheehan is described as pan-hypopituitarism secondary to pituitary necrosis after post-partum hemorrhage. The clinical condition presentation depends on the hormonal shortfall presented, and may involve changes in serum cortisol levels, thyroid function, growth hormones, breast feeding and sex hormones. Although poorly described in the literature, there are reports of dilated cardiomyopathy associated with Sheehan's syndrome, some with reversibility of cardiopathy after hormone replacement therapy. This paper reports a clinical case of Sheehan's syndrome associated to dilated cardiomyopathy that displayed cardiac function improvement after hormone replacement therapy. (author)