Published November 1993
| Version v1
Journal article
Blood extracellular DNA after irradiation
- 1. Leningradskij Gosudarstvennyj Univ., Leningrad (Russian Federation)
Description
It has been shown that blood extracellular DNA of irradiated rats largely consists of the low-molecular DNA and its oligomers. Molecular masses of oligomers are multiple to molecular mass of monomer fragment with nucleosome size. The low-molecular DNA has linear form. The average content of GC-pairs in low-molecular DNA is higher than in total rat's DNA (48.5% against 41.5%). The low-molecular DNA is a part of complex containing RNA, acidic proteins and lipids. It is assumed that the formation of low-molecular DNA is a result of Ca/Mg - dependent nuclear endonuclease action
Additional details
Additional titles
- Original title (Russian)
- Внеклеточная DNK крови после облучения
Publishing Information
- Journal Title
- Radiatsionnaya Biologiya, Radioehkologiya
- Journal Volume
- 33
- Journal Issue
- 6
- Journal Page Range
- p. 854-860.
- CODEN
- RBIREJ
INIS
- Country of Publication
- Russian Federation
- Country of Input or Organization
- Russian Federation
- INIS RN
- 25051965
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BLOOD PLASMA; CALCIUM COMPOUNDS; CHROMATIN; DNA; ELECTROPHORESIS; ENDONUCLEASES; GAMMA RADIATION; MAGNESIUM COMPOUNDS; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; RADIATION DOSES; RATS
- Descriptors DEC
- ALKALINE EARTH METAL COMPOUNDS; ANIMALS; BIOLOGICAL MATERIALS; BLOOD; BODY FLUIDS; ELECTROMAGNETIC RADIATION; ENZYMES; ESTERASES; HYDROLASES; IONIZING RADIATIONS; MAMMALS; MATERIALS; NUCLEASES; NUCLEIC ACIDS; ORGANIC COMPOUNDS; PHOSPHODIESTERASES; PROTEINS; RADIATIONS; RODENTS; SEPARATION PROCESSES; VERTEBRATES