Published March 2007 | Version v1
Journal article

p-Nitrobenzoic acid promoted synthesis of 1,5-benzodiazepine derivatives

  • 1. Indian Institute of Chemical Technology, Hyderabad (India)

Description

p-Nitrobenzoic acid was found to be the versatile Bronsted organic acid promoter among the carboxylic acids tested for the preparation of 1,5-benzodiazepine derivatives from a wide range of substituted o-phenylenediamines and ketones. The corresponding products were obtained in good isolated yields (62-92%) under mild conditions using acetonitrile as solvent at ambient temperature. Further, the reagent could be easily recovered and reused. (author)

Availability note (English)

Also available from http://www.scielo.br/pdf/jbchs/v18n2/a08v18n2.pdf

Additional details

Publishing Information

Journal Title
Journal of the Brazilian Chemical Society
Journal Volume
18
Journal Issue
2
Journal Page Range
p. 291-296
ISSN
0103-5053
CODEN
JOCSET

Optional Information

Notes
10 refs., 3 tabs., 1 scheme