Published July 1984 | Version v1
Journal article Metadata-only

In vivo observation of lens protein diffusivity in normal and x-irradiated rabbit lenses

Creators

  • 1. Oakland Univ., Rochester, MI (USA)
  • 2. Harvard Medical School, Boston, MA (USA)
  • 3. Beth Israel Hospital, Boston, MA (USA)
  • 4. Massachusetts Inst. of Tech., Cambridge (USA). Center for Materials Science and Engineering
  • 5. Massachusetts Inst. of Tech., Cambridge (USA). Dept. of Physics

Description

Using the techniques of quasielastic light scattering spectroscopy, the effect of x-irradiation on the diffusivity of lens proteins as a function of position in the lens and time after irradiation was studied in vivo. The findings were compared with those for normal lenses in vivo. The experimentally observed correlation functions show marked changes in the protein diffusivity well before substantial biochemical changes take place. (author)

Additional details

Publishing Information

Journal Title
Exp. Eye Res.
Journal Volume
39
Journal Issue
1
Series
Exp. Eye Res.
Journal Page Range
61-68
ISSN
0014-4835

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
16030376
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; CATARACTS; CRYSTALLINE LENS; DIFFUSION; IN VIVO; LASER SPECTROSCOPY; PROTEINS; RABBITS; X RADIATION
Descriptors DEC
ANIMALS; BIOLOGICAL EFFECTS; BODY; DISEASES; ELECTROMAGNETIC RADIATION; EYES; IONIZING RADIATIONS; MAMMALS; ORGANIC COMPOUNDS; ORGANS; RADIATION EFFECTS; RADIATIONS; SENSE ORGANS; SENSE ORGANS DISEASES; SPECTROSCOPY; VERTEBRATES