Published May 2, 1990 | Version v1
Journal article

Radioselective tritiation of acetanilide and para-substituted acetanilides

  • 1. Chiba Univ., (Japan). Dept. of Chemistry

Description

Acetanilide and para-substituted acetanilides were tritiated by heating with HTO in the presence of RhCl3.3H2O as a catalyst in an N,N-dimethylformamide solution at 105-107 deg C for 18 h. Under such conditions, tritium introduced into the anilide molecules was found at the adjacent ortho positions to the acetamido group with virtually 100% regioselectivity. The substituent effect on the rate of tritiation was observed. (author) 13 refs

Additional details

Publishing Information

Journal Title
Journal of Radioanalytical and Nuclear Chemistry
Journal Volume
145
Journal Issue
1
Series
J. Radioanal. Nucl. Chem. ;Letters.
Journal Page Range
29-37
ISSN
0236-5731
CODEN
JRNCD