Published January 2021 | Version v1
Journal article

Efficacy of MLC based cobalt‐60 plans: A DVH comparison and analysis with 6 MV plans

  • 1. Department of Physics, Osmania University, Hyderabad (India)
  • 2. Department of Radiation Oncology, International Cancer Centre, MGMMT, Bhimavaram (India)
  • 3. Department of Radiation Oncology, MNJ Institute of Oncology & Regional Cancer Center, Hyderabad (India)
  • 4. Department of Radiation Oncology, Mahatma Gandhi Cancer Hospital & Research Institute, Visakhapatnam (India)

Description

The purpose of this study was to compare 3D treatment plans implemented using 6 MV Linac with a retrofitted multileaf collimator (MLC) based cobalt-60 plans. In this retrospective study, DVH analysis was used to compare homogeneity of dose within the target and the dose received by critical organs. A prototype MLC designed and developed as a retrofit to current cobalt-60 teletherapy machines with a dedicated 3D treatment planning system was used. Cases representing 5 tumor sites like head & neck, glottis, lung, gall bladder, stomach were taken for the study, which were planned using Eclipse treatment planning system and treated with 6 MV photon beams. The plans were re-planned using the retrofit cobalt-60 MLC with same beam arrangement and dose prescription in Radiation Oncology planning system (ROPS). For each case, DVH data was evaluated for both types of beam energies. Conformity index (CI) and homogeneity index (HI) for target were calculated and compared. The conformal plans created using cobalt MLC for five sites were found to be similar to those planned using 6 MV photon beams. CI values close to unity reflected dose uniformity in the target volume while HI evaluated the hotspots in the target volume. It was concluded that plans created using retrofit prototype MLC developed for cobalt-60 teletherapy machines can provide dose distributions comparable to 6 MV photon beams. The prototype MLC developed can provide a promising treatment option for existing telecobalt machines in implementing conformal therapy in developing countries.

Availability note (English)

Available from http://dx.doi.org/10.1016/j.meddos.2020.09.002

Additional details

Identifiers

DOI
10.1016/j.meddos.2020.09.002;
PII
S0958394720301291;

Publishing Information

Journal Title
Medical Dosimetry
Journal Volume
46
Journal Issue
1
Journal Page Range
p. 80-85
ISSN
0958-3947

Optional Information

Copyright
Copyright (c) 2020 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.