Efficacy of MLC based cobalt‐60 plans: A DVH comparison and analysis with 6 MV plans
Creators
- 1. Department of Physics, Osmania University, Hyderabad (India)
- 2. Department of Radiation Oncology, International Cancer Centre, MGMMT, Bhimavaram (India)
- 3. Department of Radiation Oncology, MNJ Institute of Oncology & Regional Cancer Center, Hyderabad (India)
- 4. Department of Radiation Oncology, Mahatma Gandhi Cancer Hospital & Research Institute, Visakhapatnam (India)
Description
The purpose of this study was to compare 3D treatment plans implemented using 6 MV Linac with a retrofitted multileaf collimator (MLC) based cobalt-60 plans. In this retrospective study, DVH analysis was used to compare homogeneity of dose within the target and the dose received by critical organs. A prototype MLC designed and developed as a retrofit to current cobalt-60 teletherapy machines with a dedicated 3D treatment planning system was used. Cases representing 5 tumor sites like head & neck, glottis, lung, gall bladder, stomach were taken for the study, which were planned using Eclipse treatment planning system and treated with 6 MV photon beams. The plans were re-planned using the retrofit cobalt-60 MLC with same beam arrangement and dose prescription in Radiation Oncology planning system (ROPS). For each case, DVH data was evaluated for both types of beam energies. Conformity index (CI) and homogeneity index (HI) for target were calculated and compared. The conformal plans created using cobalt MLC for five sites were found to be similar to those planned using 6 MV photon beams. CI values close to unity reflected dose uniformity in the target volume while HI evaluated the hotspots in the target volume. It was concluded that plans created using retrofit prototype MLC developed for cobalt-60 teletherapy machines can provide dose distributions comparable to 6 MV photon beams. The prototype MLC developed can provide a promising treatment option for existing telecobalt machines in implementing conformal therapy in developing countries.
Availability note (English)
Available from http://dx.doi.org/10.1016/j.meddos.2020.09.002Additional details
Identifiers
- DOI
- 10.1016/j.meddos.2020.09.002;
- PII
- S0958394720301291;
Publishing Information
- Journal Title
- Medical Dosimetry
- Journal Volume
- 46
- Journal Issue
- 1
- Journal Page Range
- p. 80-85
- ISSN
- 0958-3947
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 54003132
- Subject category
- S61: RADIATION PROTECTION AND DOSIMETRY; S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BLADDER; COBALT 60; COLLIMATORS; CRITICAL ORGANS; HEAD; LINEAR ACCELERATORS; LUNGS; NECK; NEOPLASMS; PHOTON BEAMS; PLANNING; RADIATION DOSE DISTRIBUTIONS; RADIATION DOSES; RADIOTHERAPY; STOMACH
- Descriptors DEC
- ACCELERATORS; BEAMS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COBALT ISOTOPES; DIGESTIVE SYSTEM; DISEASES; DOSES; GASTROINTESTINAL TRACT; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEDICINE; MINUTES LIVING RADIOISOTOPES; NUCLEAR MEDICINE; NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIOISOTOPES; RADIOLOGY; RESPIRATORY SYSTEM; THERAPY; URINARY TRACT; YEARS LIVING RADIOISOTOPES
Optional Information
- Copyright
- Copyright (c) 2020 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.