Published August 1, 2016
| Version v1
Journal article
Nanodiamonds + bacteriochlorin as an infrared photosensitizer for deep-lying tumor diagnostics and therapy
- 1. National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), 31 Kashirskoe shosse, 115409 Moscow (Russian Federation)
- 2. A.M. Prokhorov General Physics Institute, Russian Academy of Science, Vavilov str.38, bld.5, 119991 Moscow (Russian Federation)
- 3. Lomonosov Moscow State University (MSU), Chemical faculty, 119991 Moscow (Russian Federation)
Description
The spectroscopic properties of potentially perspective nanostructure: diamond nanoparticles with a surface layer of IR-photosensitizer, bacteriochlorin, were experimentally investigated in this study. Such specific structure of the object encourages enhancement of the drug tropism to the tumor, as well as increasing of photodynamic penetration depth. The size distribution spectra of diamond nanoparticles; diamond nanoparticles, artificially covered with bacteriochlorin molecules layer, in aqueous solution, were obtained during the study. Based on the absorption and fluorescence spectra analysis, the benefits of functional nanostructure as a drug for deep-lying tumor diagnostics and therapy were reviewed. (paper)
Availability note (English)
Available from http://dx.doi.org/10.1088/1742-6596/737/1/012052Additional details
Identifiers
Publishing Information
- Journal Title
- Journal of Physics. Conference Series (Online)
- Journal Volume
- 737
- Journal Issue
- 1
- Journal Page Range
- [7 p.]
- ISSN
- 1742-6596
Conference
- Title
- 5. international conference of photonics and information optics
- Dates
- 3-5 Feb 2016
- Place
- Moscow (Russian Federation)
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 48100067
- Subject category
- S77: NANOSCIENCE AND NANOTECHNOLOGY; S60: APPLIED LIFE SCIENCES;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- ABSORPTION; AQUEOUS SOLUTIONS; DIAMONDS; DRUGS; FLUORESCENCE; FLUORESCENCE SPECTROSCOPY; LAYERS; MOLECULES; NANOPARTICLES; NANOSTRUCTURES; NEOPLASMS; PENETRATION DEPTH; SURFACES; THERAPY
- Descriptors DEC
- CARBON; DISEASES; DISPERSIONS; ELEMENTS; EMISSION; EMISSION SPECTROSCOPY; HOMOGENEOUS MIXTURES; LUMINESCENCE; MEDICINE; MINERALS; MIXTURES; NONMETALS; PARTICLES; PHOTON EMISSION; SOLUTIONS; SORPTION; SPECTROSCOPY