Published August 1, 2016 | Version v1
Journal article

Nanodiamonds + bacteriochlorin as an infrared photosensitizer for deep-lying tumor diagnostics and therapy

  • 1. National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), 31 Kashirskoe shosse, 115409 Moscow (Russian Federation)
  • 2. A.M. Prokhorov General Physics Institute, Russian Academy of Science, Vavilov str.38, bld.5, 119991 Moscow (Russian Federation)
  • 3. Lomonosov Moscow State University (MSU), Chemical faculty, 119991 Moscow (Russian Federation)

Description

The spectroscopic properties of potentially perspective nanostructure: diamond nanoparticles with a surface layer of IR-photosensitizer, bacteriochlorin, were experimentally investigated in this study. Such specific structure of the object encourages enhancement of the drug tropism to the tumor, as well as increasing of photodynamic penetration depth. The size distribution spectra of diamond nanoparticles; diamond nanoparticles, artificially covered with bacteriochlorin molecules layer, in aqueous solution, were obtained during the study. Based on the absorption and fluorescence spectra analysis, the benefits of functional nanostructure as a drug for deep-lying tumor diagnostics and therapy were reviewed. (paper)

Availability note (English)

Available from http://dx.doi.org/10.1088/1742-6596/737/1/012052

Additional details

Publishing Information

Journal Title
Journal of Physics. Conference Series (Online)
Journal Volume
737
Journal Issue
1
Journal Page Range
[7 p.]
ISSN
1742-6596

Conference

Title
5. international conference of photonics and information optics
Dates
3-5 Feb 2016
Place
Moscow (Russian Federation)

INIS

Country of Publication
United Kingdom
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
48100067
Subject category
S77: NANOSCIENCE AND NANOTECHNOLOGY; S60: APPLIED LIFE SCIENCES;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ABSORPTION; AQUEOUS SOLUTIONS; DIAMONDS; DRUGS; FLUORESCENCE; FLUORESCENCE SPECTROSCOPY; LAYERS; MOLECULES; NANOPARTICLES; NANOSTRUCTURES; NEOPLASMS; PENETRATION DEPTH; SURFACES; THERAPY
Descriptors DEC
CARBON; DISEASES; DISPERSIONS; ELEMENTS; EMISSION; EMISSION SPECTROSCOPY; HOMOGENEOUS MIXTURES; LUMINESCENCE; MEDICINE; MINERALS; MIXTURES; NONMETALS; PARTICLES; PHOTON EMISSION; SOLUTIONS; SORPTION; SPECTROSCOPY