Published October 1986 | Version v1
Journal article Metadata-only

Preparation of 13N-amines by reduction of 13N-amides

Creators

  • 1. National Inst. of Radiological Sciences, Chiba (Japan)

Description

An improved method for preparing 13N-amines by LiAlH4 reduction of 13N-amides using an organic solution of 13N-ammonia as a labelling precursor is described. Biodistribution studies of 13N-phenylethylamine and 13N-octylamine in mice show an accumulation of radioactivity in the brain and the heart. (UK)

Additional details

Publishing Information

Journal Title
J. Labelled Compd. Radiopharm.
Journal Volume
23
Journal Issue
10-12
Series
J. Labelled Compd. Radiopharm.
Journal Page Range
1116-1117
ISSN
0362-4803
CODEN
JLCRD

Conference

Title
6. international symposium on radiopharmaceutical chemistry.
Dates
29 Jun - 3 Jul 1986.
Place
Boston, MA (USA).

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
18081961
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Resource subtype / Literary indicator
Conference
Descriptors DEI
AMINES; AROMATICS; CHEMICAL PREPARATION; LABELLING; MICE; NITROGEN 13; RADIOPHARMACEUTICALS; TISSUE DISTRIBUTION
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; DISTRIBUTION; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MAMMALS; MATERIALS; MINUTES LIVING RADIOISOTOPES; NITROGEN ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RODENTS; SYNTHESIS; VERTEBRATES