Published November 1991
| Version v1
Journal article
A preliminary study on the targeting localization of human hepatocellular carcinoma grafted in nude mice with 125I labelled lectins
Creators
- 1. Inst. of Hepatobiliary Surgery, Changhai Hospital, Shanghai (China)
Description
BSAI, PSA and RCAI which can bind to glycoconjugates of hepatocellular carcinoma (HCC) were radiolabelled with 125I and the targeting localization of human HCC grafted in nude mice were observed with 125I-lectins. The results indicated that the planted human HCC in nude mice was clearly imaged with the three 125I-lectins though other tissues in the mice also contained different amounts of 125I-lectins. The planted tumors could not be showed with Na 125I or 125I-cytochrome C in controls. It is suggested that lectins specific for HCC had a potential application in the targeting localization of HCC
Additional details
Publishing Information
- Journal Title
- Chinese Journal of Nuclear Medicine
- Journal Volume
- 11
- Journal Issue
- 4
- Journal Page Range
- p. 238-240.
- ISSN
- 0253-9780
- CODEN
- CITCDE
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 24006546
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE; S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- AGGLUTININS; BIOLOGICAL LOCALIZATION; DIAGNOSIS; GRAFTS; HEPATOMAS; IMAGES; IODINE 125; LABELLED COMPOUNDS; LABELLING; LIVER; MICE
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BODY; CARCINOMAS; DAYS LIVING RADIOISOTOPES; DIGESTIVE SYSTEM; DISEASES; ELECTRON CAPTURE RADIOISOTOPES; GLANDS; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IODINE ISOTOPES; ISOTOPES; MAMMALS; NEOPLASMS; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPES; RODENTS; TRANSPLANTS; VERTEBRATES