Published July 2022 | Version v1
Journal article Metadata-only

The role of nuclear medicine imaging and therapy of brain tumors. From differential diagnosis between recurrence vs. necrosis to innovative treatment

Creators

  • 1. Hokkaido University, Graduate School of Medicine, Department of Diagnostic Imaging, Sapporo, Hokkaido (Japan)
  • 2. Hokkaido University, Graduate School of Medicine, Department of Neurosurgery, Sapporo, Hokkaido (Japan)
  • 3. Fukushima Medical University, Fukushima Global Medical Science Center, Advanced Clinical Research Center, Fukushima (Japan)
  • 4. Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT (United States)

Description

Nuclear medicine is a technique that can be used for both diagnosis and treatment. FDG PET is a widely used technique as an in-vivo image of cancer, but its physiological accumulation in normal brain tissue is problematic especially for brain tumor imaging. 11C- methionine overcomes this disadvantage, but has different drawbacks such as a short half-life. Although nuclear medicine therapy for brain tumors is still in the clinical trial stage, several radiopharmaceuticals, including beta and alpha emitters, are expected to be used for the treatment of brain tumors in the future. (author)

Availability note (English)

Available from DOI: https://doi.org/10.18888/rp.0000001997

Additional details

Additional titles

Original title (Japanese)
脳腫瘍に対する核医学の役割.再発・壊死の鑑別や核医学治療の可能性

Identifiers

DOI
10.18888/rp.0000001997;

Publishing Information

Journal Title
Rinsho Hoshasen
Journal Volume
67
Journal Issue
7
Series
雑誌名:臨床放射線
Journal Page Range
p. 683-692
ISSN
0009-9252

INIS

Country of Publication
Japan
Country of Input or Organization
Japan
INIS RN
54040537
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BRAIN; CARBON 11; FLUORINE 18; FLUORODEOXYGLUCOSE; GLIOMAS; NECROSIS; POSITRON COMPUTED TOMOGRAPHY; RADIOPHARMACEUTICALS; RADIOTHERAPY
Descriptors DEC
ANTIMETABOLITES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; CARBON ISOTOPES; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; EMISSION COMPUTED TOMOGRAPHY; EVEN-ODD NUCLEI; FLUORINE ISOTOPES; HOURS LIVING RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MATERIALS; MEDICINE; MINUTES LIVING RADIOISOTOPES; NANOSECONDS LIVING RADIOISOTOPES; NEOPLASMS; NERVOUS SYSTEM; NERVOUS SYSTEM DISEASES; NUCLEAR MEDICINE; NUCLEI; ODD-ODD NUCLEI; ORGANS; PATHOLOGICAL CHANGES; RADIOACTIVE MATERIALS; RADIOISOTOPES; RADIOLOGY; THERAPY; TOMOGRAPHY

Optional Information

Notes
39 refs., 2 figs.