Changes in T and B lymphocyte activity with the radiation damage extent in nonuniform irradiation of mice

Shielding of the head and abdomen during irradiation of mice with 7 Gy of X radiation reduced the manifestations of radiation damage and was especially strongly manifested during the repair of the damage. At different time intervals after irradiation the functional activity of T lymphocytes in the spleen was assessed as to the ability to induce the local graft-host reaction, and the functional activity of B lymphocytes was assessed according to the formation of antibodies against sheep erythrocytes. (M.D.)