Published March 1979 | Version v1
Journal article

The influence of experimental conditions on the efficiency of the labeling of 1-hydroxy-ethylidene-1,1-di-sodium phosphonate with sup(99m)Tc, using Sn(II) as the reductant

  • 1. Stichting Energieonderzoek Centrum Nederland, Petten

Description

The influence of experimental conditions on the preparation yield of the sup(99m)Tc - complex of 1-hydroxy-ethylidene-1, 1-di sodium phosphonate (EHDP) by reduction with Sn(II) ions has been investigated. Variables considered were pH (3, 5, 7 and 9), Sn(II) (10-5, 10-4 and 10-3 mol/l) and EHDP (2. 10-3 and 5. 10-2 mol/l). The results were analysed by variance methods and optimal conditions derived. Results were checked experimentally and the stability against oxidation by air and against dilution was investigated. (U.K.)

Additional details

Publishing Information

Journal Title
Int. J. Appl. Radiat. Isot.
Journal Volume
30
Journal Issue
3
Series
Int. J. Appl. Radiat. Isot.
Journal Page Range
185-187
ISSN
0020-708X