Published July 1982 | Version v1
Journal article

Direct preparation of 14C-labelled 5-allyl- and 5-propyl-2'-deoxyuridine from [2-14C]2'-deoxyuridine

  • 1. California Univ., Davis (USA). Dept. of Chemistry

Description

[2-14C]5-Allyl-2'-deoxyuridine was synthesized directly from [2-14C]2'-deoxyuridine using mercury, palladium, and 3-chloropropene. [2-14C]5-Propyl-2'-deoxyuridine was obtained by hydrogenation of the [14C]5-allyl-2'-deoxyuridine. Advantages of the synthetic method and its application to the preparation of other radiolabeled 5-alkyl/alkenyl-2'-deoxyuridines are discussed. (author)

Additional details

Publishing Information

Journal Title
J. Labelled Compd. Radiopharm.
Journal Volume
19
Journal Issue
7
Series
J. Labelled Compd. Radiopharm.
Journal Page Range
861-866