Published 1994
| Version v1
Book
Radioimmunodetection (RAID) using radiolabeled monoclonal antibodies (MoAbs) has potential clinical useful application in diagnosis and management of breast carcinoma
- 1. Buffalo Univ., NY (United States)
Description
The current study attempted to assess the potential proficiency of radioimmunodetection (RAID) of primary, residual, multicentric and recurrent breast carcinoma using two-radiolabeled murine monoclonal antibodies (MoAbs), anti-Human Milk Fat Globuli n (HMFG1) labeled with Iodine (I123) and anti-Carcinoembryonic Antigen (CEA) labeled with Technetium (Tch99). The MoAbs used bound specifically to breast cancer lesions, with accurate RAID in 10 of 12 studied patients. Accuracy 83.3%, sensitivity 87.5% and specificity 75.0%, suggesting that radiolabeled MoAbs used in this study are potential diagnostic agents for breast carcinoma
Additional details
Publishing Information
- Publisher
- Monduzzi Editore.
- Imprint Place
- Bologna (Italy)
- ISBN
- 88-323-1030-9
- Imprint Title
- Proceedings of 16th international cancer congress: Free papers and posters: New Delhi (India), October 30 - November 5, 1994
- Imprint Pagination
- v. 2.
- Journal Page Range
- p. 1291-1295.
Conference
- Title
- 16. international cancer congress.
- Dates
- 30 Oct - 5 Nov 1994.
- Place
- New Delhi (India).
INIS
- Country of Publication
- Italy
- Country of Input or Organization
- Italy
- INIS RN
- 27041237
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- CARCINOMAS; DIAGNOSIS; MAMMARY GLANDS; MONOCLONAL ANTIBODIES; RADIOIMMUNODETECTION
- Descriptors DEC
- ANTIBODIES; BODY; DIAGNOSTIC TECHNIQUES; DISEASES; GLANDS; ISOTOPE APPLICATIONS; NEOPLASMS; ORGANS; RADIOASSAY; TRACER TECHNIQUES