Published 2011 | Version v1
Journal article Metadata-only

Chemical constituents from branches of Maytenus gonoclada (Celastraceae) and evaluation of antimicrobial activity

Creators

  • 1. Universidade Federal de Minas Gerais (DQ/UFMG), Belo Horizonte (Brazil). Dept. de Quimica. Nucleo de Estudos de Plantas Medicinais
  • 2. Universidade Federal de Ouro Preto (UFOP), MG (Brazil). Escola de Farmacia

Description

Six pentacyclic triterpenes were isolated from branches of Maytenus gonoclada (Celastraceae) and all NMR data of a new compound 3-oxo-12α,29-dihydroxyfriedelane are herein reported. The stereochemistry of the new friedelane was established by bidimensional NMR (HSQC, HMBC and NOESY) data, and its molecular weight confirmed by ESI mass spectrometry. Antimicrobial activity assays using the method of disk diffusion and macrodilution were carried out against the bacteria Escherichia coli, Citrobacter freundii, and Bacillus cereus, and against the fungi Candida albicans. The triterpene 3-oxo-12α-hydroxyfriedelane showed positive result against C. albicans. (author)

Availability note (English)

Available from http://www.scielo.br/pdf/jbchs/v22n5/v22n5a18.pdf

Additional details

Identifiers

URL
http://www.scielo.br/pdf/jbchs/v22n5/v22n5a18.pdf;

Publishing Information

Journal Title
Journal of the Brazilian Chemical Society
Journal Volume
22
Journal Issue
5
Journal Page Range
p. 943-949
ISSN
0103-5053
CODEN
JOCSET

INIS

Country of Publication
Brazil
Country of Input or Organization
Brazil
INIS RN
42061347
Subject category
S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
Descriptors DEI
ACETATES; CANDIDA; CARBON 13; CHLOROFORM; ESCHERICHIA COLI; ETHANOL; HEXANE; HYDROGEN 1; LIQUID COLUMN CHROMATOGRAPHY; MASS SPECTRA; NMR SPECTRA; PERCHLORIC ACID; STEREOCHEMISTRY; TERPENES; X-RAY DIFFRACTION
Descriptors DEC
ALCOHOLS; ALKANES; BACTERIA; CARBON ISOTOPES; CARBOXYLIC ACID SALTS; CHLORINATED ALIPHATIC HYDROCARBONS; CHLORINE COMPOUNDS; CHROMATOGRAPHY; COHERENT SCATTERING; DIFFRACTION; EUMYCOTA; EVEN-ODD NUCLEI; FUNGI; HALOGEN COMPOUNDS; HALOGENATED ALIPHATIC HYDROCARBONS; HYDROCARBONS; HYDROGEN COMPOUNDS; HYDROGEN ISOTOPES; HYDROXY COMPOUNDS; INORGANIC ACIDS; INORGANIC COMPOUNDS; ISOTOPES; LIGHT NUCLEI; MICROORGANISMS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC CHLORINE COMPOUNDS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; OXYGEN COMPOUNDS; PLANTS; SCATTERING; SEPARATION PROCESSES; SPECTRA; STABLE ISOTOPES; YEASTS