Support for solid phase synthesis of oligonucleotides by radiation-induced gas phase grafting of styrene onto polytetrafluoroethylene

For application in genetic engineering the solid phase synthesis of oligonucleotides, using polymeric or silica based supports has attained increased importance. Graft polymers, obtained by gas phase grafting of PTFE-powder with styrene have some advantages compared with other supports. The preparation of these graft polymers and the application for the oligonucleotide synthesis are described. (author)