Published October 1981 | Version v1
Journal article

Leukemic iris infiltration

Creators

  • 1. Pretoria Univ. (South Africa). Dept. of Ophthalmology

Description

Description of a 4 year old girl with acute lymphatic leukeamia in total bone marrow remission, with infiltrations in iris and uveitis, complicated by hypopisn and raised intraocular pressure. A diagnostic paracentesis of the anterior chamber was performed with a cytologic diagnosis established. With radiation of the anterior segment of the eye the leukaemic infiltration of the iris, hypopion and glaucoma cleared. It appears that a barrier perhaps exists which does not allow for full penetration of the iris by cytostatics so that residual leukaemic cells remain after initial therapy

Abstract (Afrikaans)

Aantasting van die oog deur leukemie is bekend en volgens histopatologiese ondersoek word die choroied en die retina die meeste betrek. Leukemiese irisinfiltrasie is egter selde in die literatuur beskryf. Johnton en Ware het slegs 5 gevalle van geisoleerde irisaantasting in akute leukemie in die literatuur gevind. Allen en Straatsma kon slegs by 2 van 76 nekropsiee en leukemiepasiente irisaantasting aantoon. Veranderinge in die anterior segment, soos korneainfiltrasie, hifeen, choroiedale massas, konjunktivale letsels, ooglidinfiltrasie, eksoftalmos en gloukoom, kan almal inisiele tekens by 'n ongediagnoseerde leukemiepasient wees. 'n Geval word beskryf met leukemie-infiltrasie van die iris wat 'n diagnostiese voorkamerpara-sentese ondergaan het en daarna suksesvol met radioterapie behandel is

Additional details

Additional titles

Original title (Afrikaans)
Leukemiese irisinfiltrasie

Publishing Information

Journal Title
Geneeskunde (Pretoria)
Journal Volume
23
Journal Issue
10
Series
Geneeskunde (Pretoria).
Journal Page Range
664-665
ISSN
0016-643X

INIS

Country of Publication
South Africa
Country of Input or Organization
South Africa
INIS RN
13647904
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
EYES; LEUKEMIA; RADIOTHERAPY
Descriptors DEC
BODY; DISEASES; HEMIC DISEASES; MEDICINE; NEOPLASMS; ORGANS; SENSE ORGANS; THERAPY