Validation and calculation of uncertainties of the method of determination of creatinine in urine in internal dosimetry

This paper describes the methodology used Lo conduct the validation of the quantification technique of content by specLrophoLomeLry creatinine in urine sarnples of exposed workers at risk of internal counterirritant, and the sludgy of ah sources uncertainty that influence in the proceas. This technique is used Lo carry ouL Lhe normahizaLion of Lhe amount of urine to urinary 24h, necessary for dosimeLric purposes, as well as a criterion for accepLance ox rejecLion of urine specimens received by the laboraLory.