Published 1997
| Version v1
Journal article
Preparation of N-[11C]methyl-2,5-dimethoxy-4-bromo-amphetamine
- 1. Eberhardt-Karls-University, Tuebingen (Germany). Institute of Pharmacy
Description
For in vivo receptor studies N-[11C]methyl-2,5-dimethoxy-4-bromo-amphetamine, [11C]MDOB, was synthesized by the reaction of [11C]CH3I with DOB in acetonitrile. The labelling yield was determined in dependence on amount of precursor, time and temperature of the methylation reaction. During 10 to 15 minutes 60% to 70% of [11C]MDOB has been obtained at 110 deg C. (author)
Additional details
Publishing Information
- Journal Title
- Journal of Radioanalytical and Nuclear Chemistry
- Journal Volume
- 221
- Journal Issue
- 1-2
- Journal Page Range
- p. 211-212.
- ISSN
- 0236-5731
- CODEN
- JRNCDM
INIS
- Country of Publication
- Hungary
- Country of Input or Organization
- Hungary
- INIS RN
- 28071224
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- AMPHETAMINES; CARBON 11; CHEMICAL REACTION YIELD; LABELLING; RADIOPHARMACEUTICALS; SYNTHESIS; TEMPERATURE DEPENDENCE; TIME DEPENDENCE
- Descriptors DEC
- AMINES; ANALEPTICS; AUTONOMIC NERVOUS SYSTEM AGENTS; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CARBON ISOTOPES; CENTRAL NERVOUS SYSTEM AGENTS; DRUGS; EVEN-ODD NUCLEI; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MATERIALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ORGANIC COMPOUNDS; RADIOACTIVE MATERIALS; RADIOISOTOPES; SYMPATHOMIMETICS; YIELDS
Optional Information
- Notes
- 1 ref.