Hypertrophic pulmonary osteoarthropathy detected by 99mTc MDP bone scintigraphy. A case report and review of literature

Hypertrophic pulmonary osteoarthropathy is a syndrome characterized by proliferative changes in the skin and skeleton. Proliferative periostitis of the long bones, oligopolysinovitis and digital clubbing are also common. There are two types of hypertrophic osteoarthropathy, primary and secondary. Secondary hypertrophic osteoarthropathy is more common than the primary and is seen in association with many disease conditions of the cardiovascular, hepatobiliary gastrointestinal and also in malignancies. Among the malignancies, carcinoma of the lung and breast are the commonest, which produces hypertrophic osteoarthropathy. Bone scintigraphy with 99mTc MDP [Methylene Oiphosphonate] is a sensitive investigation in the detection of hypertrophic osteoarthopathy. (author)