Published January 2019 | Version v1
Journal article

Synthesis of iron oxide nanorods for enhanced magnetic hyperthermia

  • 1. Department of Chemistry, Lomonosov Moscow State University, Leninskiye Gory 1-3, GSP-1, 119991 Moscow (Russian Federation)
  • 2. National University of Science and Technology "MISIS", Leninskiy Prospect 4, 119991 Moscow (Russian Federation)
  • 3. Pirogov Russian National Research Medical University, Ostrovityanova 1, 117997 Moscow (Russian Federation)
  • 4. Dmitry Mendeleev University of Chemical Technology of Russia, Miusskaya Sq. 9, Moscow, 125047 Russian Federation (Russian Federation)

Description

Magnetic hyperthermia is one of the most effective methods for treatment of cancer. In this work we discuss synthesis of magnetic iron oxide nanorods (IONRds) and their application for enhanced magnetic hyperthermia. By microwave irradiation the monodisperse water-soluble IONRds with clear morphology were obtained. Magnetic measurements showed that such IONRds have high value of coercivity (141 Oe). Moreover, hyperthermia experiments with synthesized samples were carried out. At the frequency and field strength of alternating magnetic field (AMF) f = 261 kHz H = 20 kA m−1 the specific absorption rate (SAR) and intrinsic loss power (ILP) values were equal to 147 W g−1 and 1.4 nHm2 kg−1 respectively, which confirms the efficiency of synthesized nanorods in hyperthermia applications.

Additional details

Identifiers

DOI
10.1016/j.jmmm.2018.09.014;
PII
S0304885318319929;

Publishing Information

Journal Title
Journal of Magnetism and Magnetic Materials
Journal Volume
469
Journal Page Range
p. 443-449
ISSN
0304-8853
CODEN
JMMMDC

INIS

Country of Publication
Netherlands
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
55025765
Subject category
S36: MATERIALS SCIENCE;
Descriptors DEI
ABSORPTION; COERCIVE FORCE; HYPERTHERMIA; IRON OXIDES; IRRADIATION; MAGNETIC FIELDS; MICROWAVE RADIATION; MORPHOLOGY; NANOSTRUCTURES; NEOPLASMS
Descriptors DEC
BODY TEMPERATURE; CHALCOGENIDES; DISEASES; ELECTROMAGNETIC RADIATION; IRON COMPOUNDS; OXIDES; OXYGEN COMPOUNDS; RADIATIONS; SORPTION; TRANSITION ELEMENT COMPOUNDS

Optional Information

Copyright
Copyright (c) 2018 Elsevier B.V. All rights reserved.