Synthesis of iron oxide nanorods for enhanced magnetic hyperthermia
Creators
- 1. Department of Chemistry, Lomonosov Moscow State University, Leninskiye Gory 1-3, GSP-1, 119991 Moscow (Russian Federation)
- 2. National University of Science and Technology "MISIS", Leninskiy Prospect 4, 119991 Moscow (Russian Federation)
- 3. Pirogov Russian National Research Medical University, Ostrovityanova 1, 117997 Moscow (Russian Federation)
- 4. Dmitry Mendeleev University of Chemical Technology of Russia, Miusskaya Sq. 9, Moscow, 125047 Russian Federation (Russian Federation)
Description
Magnetic hyperthermia is one of the most effective methods for treatment of cancer. In this work we discuss synthesis of magnetic iron oxide nanorods (IONRds) and their application for enhanced magnetic hyperthermia. By microwave irradiation the monodisperse water-soluble IONRds with clear morphology were obtained. Magnetic measurements showed that such IONRds have high value of coercivity (141 Oe). Moreover, hyperthermia experiments with synthesized samples were carried out. At the frequency and field strength of alternating magnetic field (AMF) f = 261 kHz H = 20 kA m−1 the specific absorption rate (SAR) and intrinsic loss power (ILP) values were equal to 147 W g−1 and 1.4 nHm2 kg−1 respectively, which confirms the efficiency of synthesized nanorods in hyperthermia applications.
Additional details
Identifiers
- DOI
- 10.1016/j.jmmm.2018.09.014;
- PII
- S0304885318319929;
Publishing Information
- Journal Title
- Journal of Magnetism and Magnetic Materials
- Journal Volume
- 469
- Journal Page Range
- p. 443-449
- ISSN
- 0304-8853
- CODEN
- JMMMDC
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 55025765
- Subject category
- S36: MATERIALS SCIENCE;
- Descriptors DEI
- ABSORPTION; COERCIVE FORCE; HYPERTHERMIA; IRON OXIDES; IRRADIATION; MAGNETIC FIELDS; MICROWAVE RADIATION; MORPHOLOGY; NANOSTRUCTURES; NEOPLASMS
- Descriptors DEC
- BODY TEMPERATURE; CHALCOGENIDES; DISEASES; ELECTROMAGNETIC RADIATION; IRON COMPOUNDS; OXIDES; OXYGEN COMPOUNDS; RADIATIONS; SORPTION; TRANSITION ELEMENT COMPOUNDS
Optional Information
- Copyright
- Copyright (c) 2018 Elsevier B.V. All rights reserved.