Published 1975
| Version v1
Book
Psoralen cross-links in DNA: biological consequence and cellular repair
Description
Psoralens, or furocoumarins, are a class of compounds particularly noted for their sensitizing action on organisms and nucleic acids in the presence of lung wavelength ultraviolet light. The molecular basis for the photosensitizing action of psoralens appears to be a consequence of their binding rather specifically to native DNA in the presence of light, forming adducts to single strands and interstrand cross-links. The role of cross-links in the repair of DNA is discussed
Additional details
Publishing Information
- Publisher
- Academic Press, Inc.
- Imprint Place
- New York
- Imprint Title
- Radiation research. Biomedical, chemical, and physical perspectives
- Imprint Pagination
- p. 582-589.
Conference
- Title
- 5. international radiation research congress meeting.
- Dates
- 14 Jul 1974.
- Place
- Seattle, Washington, USA.
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 8289927
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; BIOLOGICAL REPAIR; DNA; ESCHERICHIA COLI; IRRADIATION; PSORALEN; RADIOSENSITIVITY; ULTRAVIOLET RADIATION
- Descriptors DEC
- ANTICOAGULANTS; BACTERIA; BIOLOGICAL EFFECTS; BIOLOGICAL RECOVERY; DRUGS; ELECTROMAGNETIC RADIATION; HETEROCYCLIC COMPOUNDS; MICROORGANISMS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; ORGANIC OXYGEN COMPOUNDS; RADIATION EFFECTS; RADIATIONS
Optional Information
- Notes
- Imprint:See CONF-740715--.