Published June 1981
| Version v1
Report
Initial kinetics and cumulative biodistribution of Tc-99m-diethyl IDA in a mammalian animal model
- 1. Univ. of Nebraska Medical Center, Omaha
Description
The early kinetic behavior and cumulative biodistribution of Tc-99m-N-α-(2,6-diethyl acetanalide) iminodiacetic acid have been described in a mammalian (rabbit) model as a basis for dosimetric considerations of this hepatobiliary agent. These data were obtained from in vivo region of interest time activity curves generated by automated data processing techniques from the initial distribution and localization of the radiopharmaceutical. Subsequently, using classic biodistribution techniques, tissue analysis of the percentage of administered dose per tissue or organ was determined
Additional details
Publishing Information
- Imprint Title
- Third international radiopharmaceutical dosimetry symposium
- Journal Page Range
- p. 413-420.
- Report number
- FDA--81-8166
Conference
- Title
- ORAU radiopharmaceutical dosimetry symposium.
- Dates
- 6 - 10 Oct 1980.
- Place
- Oak Ridge, TN (USA).
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 14731836
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- BILIARY TRACT; BIOLOGICAL MODELS; CHEMICAL PREPARATION; DATA PROCESSING; DISTRIBUTION; DOSIMETRY; IMINES; ISOMERIC NUCLEI; KIDNEYS; LIVER; RABBITS; RADIONUCLIDE KINETICS; RADIOPHARMACEUTICALS; SCINTISCANNING; TECHNETIUM 99; TISSUES
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DRUGS; GLANDS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; KINETICS; LABELLED COMPOUNDS; MAMMALS; MATERIALS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; RADIOACTIVE MATERIALS; RADIOISOTOPE SCANNING; RADIOISOTOPES; SYNTHESIS; TECHNETIUM ISOTOPES; VERTEBRATES; YEARS LIVING RADIOISOTOPES