Published October 14, 2019 | Version v1
Journal article

Nickel-catalyzed conversion of enol triflates into alkenyl halides

  • 1. The Warren and Katharine Schlinger Laboratory of Chemistry and Chemical Engineering, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA (United States)

Description

A Ni-catalyzed halogenation of enol triflates was developed and it enables the synthesis of a broad range of alkenyl iodides, bromides, and chlorides under mild reaction conditions. The reaction utilizes inexpensive, bench-stable Ni(OAc)2⋅4 H2O as a precatalyst and proceeds at room temperature in the presence of sub-stoichiometric Zn and either 1,5-cyclooctadiene or 4-(N,N-dimethylamino)pyridine. (© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim)

Availability note (English)

Available from: http://dx.doi.org/10.1002/anie.201906815

Additional details

Identifiers

Publishing Information

Journal Title
Angewandte Chemie (International Edition)
Journal Volume
58
Journal Issue
42
Journal Page Range
p. 14901-14905
ISSN
1433-7851
CODEN
ACIEF5