Published October 2006 | Version v1
Journal article Metadata-only

Significance of changes of serum TPOAb and TRAb levels in patients with Graves' disease (GD)

Creators

  • 1. Dept. of RIA, Nanjing Genral Hospital of Nanjing Military Area Command, PLA, Nanjing (China)

Description

Objective: To investigate the significance of changes of serum TPOAb and TRAb levels in patients with Graves' dis- ease (GD). Methods: Serum TPOAb (with RIA) and TRAb (with RRA) levels were determined in 27 patients with Graves' disease, before treatment 10 patients with Graves' disease clinically cured and 35 controls. Results: The serum levels and positive rates of TPOAb and TRAb in patients with Graves' disease before treatment were significantly higher than those in the patients with Graves' disease clinically cured and controls (P<0.01). Conclusion: TPOAb and TRAb were involved in the pathogenesis of Graves' dis- ease and could be used as diagnostic and treatment indicators. (authors)

Additional details

Publishing Information

Journal Title
Journal of Radioimmunology
Journal Volume
19
Journal Issue
5
Journal Page Range
p. 361-362
ISSN
1008-9810

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
39096097
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
ANTIBODIES; DIAGNOSIS; HYPERTHYROIDISM; PATHOGENESIS; PATIENTS; PEROXIDASES; RADIOIMMUNOASSAY; RADIORECEPTOR ASSAY; RECEPTORS; THYROID; TSH
Descriptors DEC
BIOASSAY; BODY; DIAGNOSTIC TECHNIQUES; DISEASES; ENDOCRINE DISEASES; ENDOCRINE GLANDS; ENZYMES; GLANDS; HORMONES; IMMUNOASSAY; ISOTOPE APPLICATIONS; MEMBRANE PROTEINS; ORGANIC COMPOUNDS; ORGANS; OXIDOREDUCTASES; PEPTIDE HORMONES; PITUITARY HORMONES; PROTEINS; RADIOASSAY; RADIOIMMUNODETECTION; TRACER TECHNIQUES

Optional Information

Notes
1 tab., 4 refs.