Published May 1985
| Version v1
Journal article
Plasma transport of sup(99m)Tc-p-butyl-IDA
- 1. Centre Hospitalier Universitaire, 42 - Saint-Etienne (France). Service Central de Medecine Nucleaire
Description
Plasma transport of sup(99m)Tc-p-butyl-IDA was measured by four in vitro methods: trichloroacetic acid precipitation, electrophoresis, HPLC, and Scatchard binding isotherm. The data are in accord with protein transport, the main carrier being albumin with two categories of sites. This work suggests that after IV injection of sup(99m)Tc-p-butyl-IDA in humans plasma protein binding is one of the limiting factors for the hepatic deposition of the radiopharmacentical. (orig.)
Additional details
Publishing Information
- Journal Title
- Eur. J. Nucl. Med.
- Journal Volume
- 10
- Journal Issue
- 9/10
- Series
- CODEN: EJNMD.;Eur. J. Nucl. Med.
- Journal Page Range
- 437-440
- ISSN
- 0340-6997
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 16049966
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BLOOD PLASMA; CHROMATOGRAPHY; ELECTROPHORESIS; IN VITRO; INTRAVENOUS INJECTION; ISOMERIC NUCLEI; ISOTHERMS; KINETICS; PATIENTS; RADIOPHARMACEUTICALS; TECHNETIUM COMPLEXES; TECHNETIUM 99; TRANSLOCATION
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BODY FLUIDS; COMPLEXES; DRUGS; HOURS LIVING RADIOISOTOPES; INJECTION; INTAKE; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MATERIALS; NUCLEI; ODD-EVEN NUCLEI; RADIOACTIVE MATERIALS; RADIOISOTOPES; SEPARATION PROCESSES; TECHNETIUM ISOTOPES; TRANSITION ELEMENT COMPLEXES; YEARS LIVING RADIOISOTOPES