Clinical Significance of the Measurements of Serum HA, PC-III,IV-C and LN in the Patients with Chronic Liver Diseases
Creators
- 1. Department of Nuclear Medicine, the Central Hospital of Datun, Xuzhou (China)
Description
To explore the clinical value of serum hyaluronic acid (HA), type III precollagen(PC-III), type IV precollagen (IV-C), and laminin (LN) in patients with chronic liver diseases. The serum levels of HA, PC-III, IV-C and LN were determined by RIA in 578 patients with chronic liver diseases. The results showed that the serum levels of HA, PC-III, IV-C and LN in patients with chronic liver diseases were positively correlated with the severer degree of chronic liver disease. The serum HA, PC-III, IV-C and LN reached highest level on the stage of hepatic cirrhosis. The changes of these serum markers were corresponding with the severer degree of chronic liver disease. The serum HA, PC-III, IV-C and LN could be regarded as markers in the diagnosis of hepatic fibrosis in the patients with chronic liver diseases. (authors)
Additional details
Publishing Information
- Journal Title
- Labeled Immunoassays and Clinical Medicine
- Journal Volume
- 17
- Journal Issue
- 2
- Journal Page Range
- p. 74-76
- ISSN
- 1006-1703
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 43085219
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BLOOD SERUM; COLLAGEN; DIAGNOSIS; FIBROSIS; HEPATITIS; HYALURONIC ACID; LIVER; PATIENTS; PROTEINS; RADIOIMMUNOASSAY
- Descriptors DEC
- AMINES; BIOASSAY; BIOLOGICAL MATERIALS; BLOOD; BLOOD PLASMA; BODY; BODY FLUIDS; CARBOHYDRATES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DIGESTIVE SYSTEM DISEASES; DISEASES; GLANDS; IMMUNOASSAY; ISOTOPE APPLICATIONS; MATERIALS; MUCOPOLYSACCHARIDES; ORGANIC COMPOUNDS; ORGANS; PATHOLOGICAL CHANGES; POLYSACCHARIDES; PROTEINS; RADIOASSAY; RADIOIMMUNODETECTION; SACCHARIDES; SCLEROPROTEINS; TRACER TECHNIQUES
Optional Information
- Notes
- 1 tabs., 7 refs.