Published January 3, 1994 | Version v1
Journal article

Single molecule detection and photochemistry on a surface using near-field optical excitation

  • 1. Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States)

Description

We report the first photobleaching experiments of single molecules on a surface. Single molecules of rhodamine 6G are detected on a silica surface under ambient conditions using near-field scanning optical microscopy. Photobleaching of an individual molecule appears as an abrupt disappearance of fluorescence after seconds of constant excitation. Other reversible, upward and downward changes in fluorescence are observed, possibly due to reorientation of molecules on the surface

Additional details

Publishing Information

Journal Title
Physical Review Letters
Journal Volume
72
Journal Issue
1
Journal Page Range
p. 160-163.
ISSN
0031-9007
CODEN
PRLTAO