Published July 1, 2009 | Version v1
Journal article Metadata-only

Molecular mechanism of pore creation in bacterial membranes by amyloid proteins

Creators

  • 1. San Diego Supercomputer Center, University of California at San Diego, La Jolla, CA 92093-0505 (United States)
  • 2. Department of Neurosciences, University of California at San Diego, La Jolla, CA 92093-0505 (United States)

Description

This study explores the mechanism of pore creation in cellular membranes by MccE92 bacterial proteins. The results of this study are then compared with the mechanism of alpha-synuclein (aS)-based pore formation in mammalian cells, and its role in Parkinson's disease.

Availability note (English)

Available from http://dx.doi.org/10.1088/1742-6596/180/1/012026

Additional details

Identifiers

DOI
10.1088/1742-6596/180/1/012026;

Publishing Information

Journal Title
Journal of Physics. Conference Series (Online)
Journal Volume
180
Journal Issue
1
Journal Page Range
[9 p.]
ISSN
1742-6596

Conference

Title
SciDAC 2009 conference
Dates
14-18 Jun 2009
Place
San Diego, CA (United States)

INIS

Country of Publication
United Kingdom
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
42027771
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S60: APPLIED LIFE SCIENCES;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ANIMAL CELLS; BACTERIA; CELL MEMBRANES; COMPARATIVE EVALUATIONS; COMPUTERIZED SIMULATION; MEMBRANE PORES; NERVOUS SYSTEM DISEASES; PROTEINS
Descriptors DEC
CELL CONSTITUENTS; DISEASES; EVALUATION; MEMBRANES; MICROORGANISMS; ORGANIC COMPOUNDS; SIMULATION