Monitoring the effect of sweat matrix on the interaction of selected nanoparticles with DNA

Using cyclic voltammetry (CV) a differential pulse voltammetry (DPV) monitored the investigation of the possibility of electrochemical detection of TiO₂ and Al₂O₃ interactions with NPs biomacromolecule of DNA in the biological environment (RSw) and synthetic (SSw) sweat matrices using electrochemical DNA biosensor and biosensing method. By Al₂O₃ NPs were observed more significant DNA biosensor damage with increasing incubation time. From CV records of the UV radiation effect on the interaction of the matrix SSw and RSw with Al₂O₃ and TiO₂ NPs using DNA biosensor is irradiated after 15 minutes proved to be the most significant DNA damage induced by Al₂O₃ NPs in SSw environment. Method biosensing was recorded by DPV significant DNA damage in the SSw environment after exposure to UV radiation for both types of nanoparticles. (authors)