Published July 1, 1981 | Version v1
Journal article

General acid catalysis of alcohol heterolysis

  • 1. Univ. of California, Santa Barbara

Description

The conversion of diferrocenylphenylmethanol (5) into the carbocation is general acid catalyzed in H2O:CH3CN, 1:1 w/w, and α = 0.88. The corresponding reaction of tropyl alcohol is also general acid catalyzed, and α = 0.71 and 0.90 in water and H2O:CH3CN, 1:1 w/w, respectively. However, the hydrogen ion catalyzed reactions have inverse solvent kinetic hydrogen isotope effects, and k/sub H20//k/sub D20/ = 0.56 for reaction of 5 in H2O(D2O):CH3CN. Consideration of the equilibrium constants for alcohol protonation suggests that acid-catalyzed conversion of alcohol into carbocation should go from stepwise to concerted as the stability of the carbocation is increased

Additional details

Publishing Information

Journal Title
J. Am. Chem. Soc.
Journal Volume
103
Journal Issue
13
Series
J. Am. Chem. Soc.
Journal Page Range
3855-3858
ISSN
0002-7863