Published 1988 | Version v1
Journal article

Radiation-induced crosslinks between thymine and 2-D-deoxyerythropentose

  • 1. National Bureau of Standards, Gaithersburg, MD (USA)

Description

Hydroxyl radicals generated by ionizing radiation in aqueous solutions of thymine (Thy) and 2-D-deoxyerythropentose (dR) induce crosslinking between Thy and dR. The crosslinked products were identified by gas chromatography - mass spectrometry (GC-MS) and their yields determined by GC. The mechanisms of their formation are discussed and may serve as a model for radiation-induced or free-radical induced intra-DNA crosslinks. (author)

Additional details

Publishing Information

Journal Title
Radiation Physics and Chemistry
Journal Volume
32
Journal Issue
6
Series
Radiat. Phys. Chem.
Journal Page Range
731-734
ISSN
0146-5724
CODEN
RPCHD