Published 1975 | Version v1
Journal article Metadata-only

Heat-accelerated radioinactivation of attenuated poliovirus

Creators

  • 1. Sandia Labs., Albuquerque, N.Mex. (USA)

Description

Attenuated poliovirus is inactivated in a synergistic manner when exposed simultaneously to heat and ionizing radiation. The synergistic response is observed in both the thermally labile and stable forms of the virus. A three-term kinetic model may be used to describe the inactivation response of the virus in a thermal and/or ionizing radiation environment. (orig.)

Abstract (German)

Abgeschwaechte Polioviren werden synergistisch inaktiviert, wenn man sie gleichzeitig Waerme und ionisierender Strahlung aussetzt. Die synergistische Reaktion ist in der thermisch labilen wie in der stabilen Form des Virus festzustellen. Die Inaktivierung des Virus in einer Umgebung mit Waerme- und/oder ionisierender Strahlung kann in einem kinetischen Modell mit drei Terms dargestellt werden. (orig./AK)

Additional details

Identifiers

DOI
10.1007/bf01327346;

Publishing Information

Journal Title
Radiation and Environmental Biophysics
Journal Volume
12
Journal Issue
3
Series
Radiat. Environ. Biophys.
Journal Page Range
187-195
ISSN
0301-634X

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
7251324
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
COBALT 60; DOSE-RESPONSE RELATIONSHIPS; GAMMA RADIATION; HEAT TREATMENTS; KINETIC EQUATIONS; POLIO VIRUS; RADIATION DOSE UNITS; RADIOSENSITIVITY; RNA; SURVIVAL CURVES
Descriptors DEC
BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; COBALT ISOTOPES; ELECTROMAGNETIC RADIATION; EQUATIONS; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IONIZING RADIATIONS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MICROORGANISMS; MINUTES LIVING RADIOISOTOPES; NUCLEI; NUCLEIC ACIDS; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; PARASITES; RADIATIONS; RADIOISOTOPES; UNITS; VIRUSES; YEARS LIVING RADIOISOTOPES

Optional Information

Notes
4 figs.; 1 tab.; 13 refs.; Updated automatically by Metadata and Full-Text Enrichment Agent