Urinary bladder carcinoma associated with Paget's disease of skull: imaging findings on 99mTc-MDP bone scintigraphy, 18F-fluoride PET/CT and 18F-FDG PET/CT

We report the imaging findings of a patient with Paget's disease in metastatic carcinoma bladder evaluated by 99mTc-Methylene diphosphonate (MDP) bone scintigraphy, 18F-Fluoride positron emission tomography/computed tomography (PET/CT) and 18F-fluorodeoxy glucose (FDG) PET/CT. 99mTc-MDP bone scan showed intense uptake in the skull bones without any other abnormal tracer distribution. 18F-Fluoride PET/CT revealed intense uptake in the pelvic bones along with skull bones, but 18F-FDG PET/CT showed intense multifocal FDG uptake in the bladder and bilateral inguinal lymph nodes, with no abnormal uptake in the skull bones. CT images showed thickening of skull bones. (author)